stadio: Cajun Field Round: 1
Home Manager: Billy Napier Away Manager: Terry Bowden
| NCAAF | 2020/11/28 20:00 | Lafayette v UL Monroe | L | 70-20 |
| NCAAF | 2019/12/01 00:30 | UL Monroe v Lafayette | L | 30-31 |
| NCAAF | 2018/11/24 20:00 | Lafayette v UL Monroe | L | 31-28 |
| NCAAF | 2017/09/23 21:00 | UL Monroe v Lafayette | W | 56-50 |
| NCAAF | 2016/12/03 20:00 | Lafayette v UL Monroe | L | 30-3 |
| NCAAF | 2015/10/31 21:00 | Lafayette v UL Monroe | L | 30-24 |
| NCAAF | 2014/11/16 00:00 | UL Monroe v Lafayette | L | 27-34 |
| NCAAF | 2012/11/03 12:00 | UL Monroe v Lafayette | L | 24-40 |
| NCAAF | 2021/11/21 02:00 | UL Monroe v LSU | L | 14-27 |
| NCAAF | 2021/11/13 22:00 | Arkansas State v UL Monroe | L | 27-24 |
| NCAAF | 2021/11/06 19:00 | UL Monroe v Texas State | L | 19-27 |
| NCAAF | 2021/10/30 19:30 | UL Monroe v Appalachian St | L | 28-59 |
| NCAAF | 2021/10/23 23:00 | South Alabama v UL Monroe | W | 31-41 |
| NCAAF | 2021/10/16 23:00 | Libertay v UL Monroe | W | 28-31 |
| NCAAF | 2021/10/10 00:00 | Georgia State v UL Monroe | L | 55-21 |
| NCAAF | 2021/10/02 18:30 | UL Monroe v Coastal Carolina | L | 6-59 |
| NCAAF | 2021/11/20 21:00 | Lafayette v Libertay | W | 42-14 |
| NCAAF | 2021/11/20 17:00 | Lafayette v Lehigh | L | 10-17 |
| NCAAF | 2021/11/13 20:30 | Lafayette v Troy | W | 35-21 |
| NCAAF | 2021/11/13 17:30 | Colgate v Lafayette | L | 20-13 |
| NCAAF | 2021/11/06 16:30 | Lafayette v Holy Cross | L | 10-35 |
| NCAAF | 2021/11/04 23:30 | Georgia State v Lafayette | W | 17-21 |
| NCAAF | 2021/10/30 16:30 | Lafayette v Georgetown | W | 24-23 |
| NCAAF | 2021/10/30 16:00 | Texas State v Lafayette | W | 0-45 |