stadio: Hancock Stadium Round: 1
Home Manager: Brock Spack Away Manager: Mark Farley
| NCAAF | 2021/03/06 22:00 | Illinois State v Northern Iowa | W | 10-20 |
| NCAAF | 2019/11/02 17:00 | Northern Iowa v Illinois State | W | 27-10 |
| NCAAF FCS | 2018/11/03 18:00 | Illinois State v Northern Iowa | W | 16-26 |
| NCAAF | 2014/12/06 19:00 | Illinois State v Northern Iowa | L | 41-21 |
| NCAAF | 2021/10/30 21:00 | SO Illinois v Northern Iowa | W | 16-23 |
| NCAAF | 2021/10/23 19:00 | Northern Iowa v South Dakota State | W | 26-17 |
| NCAAF | 2021/10/16 21:00 | South Dakota v Northern Iowa | L | 34-21 |
| NCAAF | 2021/10/09 18:00 | Northern Iowa v North Dakota State | L | 20-34 |
| NCAAF | 2021/10/02 21:00 | Youngstown State v Northern Iowa | W | 7-34 |
| NCAAF | 2021/09/12 01:00 | Northern Iowa v CS Sacramento | W | 34-16 |
| NCAAF | 2021/09/04 20:30 | Northern Iowa v Iowa State | L | 10-16 |
| NCAAF | 2021/04/10 21:00 | North Dakota State v Northern Iowa | L | 23-20 |
| NCAAF | 2021/10/30 20:00 | Illinois State v Western Illinois | L | 31-38 |
| NCAAF | 2021/10/23 18:00 | Illinois State v South Dakota | W | 20-14 |
| NCAAF | 2021/10/16 19:00 | North Dakota State v Illinois State | L | 20-0 |
| NCAAF | 2021/10/02 18:00 | Missouri St v Illinois State | L | 41-20 |
| NCAAF | 2021/09/25 19:00 | Illinois State v SO Illinois | L | 17-35 |
| NCAAF | 2021/09/18 23:00 | Illinois State v Eastern Illinois | W | 31-24 |
| NCAAF | 2021/09/11 21:00 | Illinois State v Western Michigan | L | 0-28 |
| NCAAF | 2021/09/04 23:30 | Butler v Illinois State | W | 7-49 |